By Theresa Edwards Makrush
Researchers at UF Health Proton Therapy Institute have reported that for women with breast cancer, proton therapy can significantly reduce and in some cases nearly eliminate the dose to the heart, even when the lymph nodes overlying the heart need to be treated. In addition, proton therapy may reduce the exposure of the lung by 30 percent to 50 percent and provide better dose coverage to the lymph node regions as compared with conventional radiation.
These early results are from a pilot study conducted at the UF Health Proton Therapy Institute and published last month. Initial Report of a Prospective Dosimetric and Clinical Feasibility Trial Demonstrates Potential of Protons to Increase the Therapeutic Ratio in Breast Cancer Compared with Photons. (May 2016, International Journal of Radiation Oncology Biology Physics)
Eighteen women, nine with left-sided breast cancer and nine with right-sided breast cancer, were enrolled in the prospective study and followed for 20 months by lead researcher Julie A. Bradley, M.D., a radiation oncologist at the UF Health Proton Therapy Institute and faculty member at the University of Florida College of Medicine’s Department of Radiation Oncology.
In every patient, the proton plan was superior to the conventional plan in reducing the amount of radiation to the heart and lungs.
To learn more, click to read an interview with Dr. Bradley about the study.